Permission is granted to copy, distribute andor modify this document under the terms of the gnu free documentation license, version 1. May 24, 2009 apoptosis y ciclo celular ucsm biologia genetica molecular slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Abstract the phenomenon of apoptosis, and a number of techniques for its identification and quantification, are. Figura 3 ativacao da apoptose pelas vias extrinseca e intrinseca 41. The image below shows the main parameters of apoptosis and the approximate relative time when they are likely to be detected. Apoptosis via intrinseca y extrinseca bcl 2 apoptosis. Video apoptosis, via intrinseca y extrinseca 3er semestre. Apoptosis is an integral part of normal tissue development and homeostasis, eliminating redundant cells during embryogenesis. Donuts run away from wolf colors song, vegetables song nursery rhymes kids songs babybus duration.
Apr 05, 2015 donuts run away from wolf colors song, vegetables song nursery rhymes kids songs babybus duration. This quiz and worksheet combo helps you gauge your understanding of apoptosis. Intrinsic apoptosis an overview sciencedirect topics. However, excessive apoptosis may cause atrophy shrinking or shriveling, while lack of apoptosis in the body can lead to cancer and uncontrolled cell proliferation. From its early conceptual beginnings in the 1950s, it has exploded as an area of research within the life sciences community. It is mandatory to procure user consent prior to running these cookies on your website.
Estudo comparativo do perfil apoptotico ativado pelas vias. The caspases can be activated through either the intrinsic mitochondrial mediated or extrinsic death receptor mediated apoptotic pathways. Mechanisms of tamoxifeninduced apoptosis springerlink. Weis department of zoology, oregon state university, corvallis, or 97331, usa. Descargue como docx, pdf, txt o lea en linea desde scribd. Details you will need to know to pass the quiz include a cell that divides on its own.
University of groningen mechanisms of oxidative stress. Accumulation of misfolded proteins leads to er stress which ends with apoptosis. Tamoxifen tam has been used in the treatment of breast cancer for over a decade. Molecular mechanisms of apoptosis cell death by apoptosis occurs when a specialised intracellular signalling pathway is activated and kills the cell. In human body, the destruction of cells can be of two types namely necrosis or apoptosis. Summary this study was aimed at detecting apoptosis as a postphagocytic mechanism of symbiont selection. Apoptosis as a postphagocytic winnowing mechanism in a. Apoptosis is a type of programmed cell death in multicellular organisms. The observed clinical efficacy of tam has been attributed to both growth arrest and induction of apoptosis within the breast cancer cells. This can be activated by different stimuli, such as dna damage, cytokines, extracellular matrix loss, etc. Although the primary mechanism of action of tam is believed to be through the inhibition of estrogen receptor er, research over the years has indicated that additional, non. Apoptosis via intrinseca y extrinseca bcl 2 apoptosis scribd. Although the primary mechanism of action of tam is believed to be through the inhibition of estrogen receptor er, research over the years has indicated that additional. Via their prodomains, the initiator caspases are recruited to and activated at death inducing signalling complexes either in response to the ligation of cell surface death receptors extrinsic apoptosis pathways or in response to signals originating from inside the cell intrinsic apoptosis pathways.
Cell death in viral infections that induce apoptosis such as hiv and adenovirus or by the host immune response such as hepatitis. Apoptosis as a postphagocytic winnowing mechanism in a coraldino. Abstract apoptosis is a process whereby multiple events occur at different times. It should be stressed that apoptosis is a welldefined and possibly the most frequent form of programmed cell death, but that other, nonapoptotic types of cell death also might be of biological significance leist, 2001. Apoptosis is also called as programmed cell death, a process by which the cells are destroyed. It is a natural mechanism by which a cell intentionally destroys itself without causing damage to the organism. However, it has been reported that p53 can upregulate autophagy to maintain cell survival. Asi, reconocido por linfocitos activados inducen apoptosis en esas cels. If you continue browsing the site, you agree to the use of cookies on this website. We suggest that f2induced cell death in breast cscs is associated with intrinsic apoptosis and protective autophagy via the activation of p53, which is a wellknown tumor suppressor that induces cell cycle arrest and apoptosis fridman and lowe, 2003. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Apoptosis in pathologic conditions dna damage due to radiation, chemotherapy.
Necrosis is caused due to external agents like bacteria or virus or other substances. Apoptosis is a programmed form of cell death involving the degradation of cellular constituents by a group of cysteine proteases called caspases. Apoptosis as a postphagocytic winnowing mechanism in a coral. Pdf neuronal migration, apoptosis and bipolar disorder. Baixe no formato pptx, pdf, txt ou leia online no scribd. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as nonnecessary cookies. Initially, the ability of manganese to induce apoptosis in hematopoietic cancer cell. Summary this study was aimed at detecting apoptosis as.